Using 'Wildcards' is a database search technique where you use an asterisk ( * ) - though in some databases it can be a different character - to insert within one of your keywords to tell the database that you'll take as a result any variation of letters within that word.
Why would you ever need to do this, though? There are words in American and British English that mean the same , but are spelled differently. Using a wildcard in your search may get you more results. (Obviously, you need to know first of all that there are variant spellings, but if you do know, this is a useful technique.)
Example 1:
American = pediatrician
British = paediatrician
So, search = p*diatrician
Example 2:
American = counselor
British = counsellor
So, search = counse*or
Example 3:
American = defense
British = defence
So, search = defen*e